Table 1. Clinicopathological characteristics of colorectal PM/HM vs. PM only.
| Characteristic | PM/HM (n=11) | PM only (n=22) | P-value |
|---|---|---|---|
| Date of treatment (month-year) | 0.8 | ||
| First treatment | May-1999 | Mar-1994 | |
| Last treatment | Sept-2010 | Oct-2009 | |
| Median treatment for the group | Mar-2007 | Jan-2008 | |
| Gender (n) | 0.4 | ||
| Male | 2 | 7 | |
| Female | 9 | 15 | |
| Mean age, years | 60 | 57 | 1.0 |
| Lymph node status (n) | 0.5 | ||
| Positive | 8 | 14 | |
| Negative | 3 | 6 | |
| Not reported | 0 | 2 | |
| Tumour differential grade (n) | 0.06 | ||
| Well | 0 | 2 | |
| Moderate | 10 | 13 | |
| Poor | 0 | 7 | |
| Not reported | 1 | 0 | |
| Mucinous tumour (n) | 5 | 11 | 0.8 |
| Tumour origin (n) | 1.0 | ||
| Colon | 9 | 18 | |
| Rectum | 2 | 4 | |
| Peritoneal cancer index | |||
| Mean value (range) | 13 [3-36] | 13 [4-37] | 1.0 |
| Prior surgical score (n) | 0.6 | ||
| 0 | 2 | 2 | |
| 1 | 1 | 4 | |
| 2 | 3 | 9 | |
| 3 | 5 | 7 | |
| Not reported | 0 | 0 | |
| Synchronous disease (n) | 0.8 | ||
| Yes | 8 | 15 | |
| No | 3 | 7 | |
| IPC treatment (n) | 1.0 | ||
| HIPEC [+EPIC] | 7 [3] | 14 [10] | |
| SPIC | 4 | 8 | |
| Median number of treatments | 3 | 3 | 1.0 |
| Preoperative chemotherapy (n) | 0.1 | ||
| Yes | 10 | 13 | |
| 1st line or neoadjuvant | 10 | 13 | |
| 2nd line | 2 | 2 | |
| 3rd line | 1 | 1 | |
| No | 1 | 9 | |
| Adjuvant chemotherapy (n) | 0.8 | ||
| Yes | 4 | 7 | |
| No | 6 | 14 | |
| Not reported | 1 | 1 |
Abbreviations: HIPEC, hyperthermic intraperitoneal chemotherapy; SPIC, sequential postoperative intraperitoneal chemotherapy; EPIC, early postoperative intraperitoneal chemotherapy; PM, peritoneal metastases; HM, hepatic metastases