Table 4. Comparison of studies reporting outcome in combined treatment of PM and HM.
Median overall survival (months) | 3 year overall survival/disease free survival | Mean PCI/median number of HM | |
---|---|---|---|
Carmignani et al. (2) | |||
All patients (n=27)a | 15 | 18%/N/A | N/A |
R1 resections (n=15)a | 21 | 25%/ N/A | N/A |
Elias et al. (3) 2006 | |||
All patients (n=24) | 32 | 41%/24% | 8.6/3.6 |
Kianmanesh et al. (4) | |||
All patients (n=16) | 36 | N/A/N/A | N/A |
Chua et al. (6) | |||
R1 resections (n=16)c | Not reachedd | 55%d / N/A | 8/2 |
Varban et al. (5) | |||
All patients (n=14) | 23 | 28%/N/A | N/A/1 |
R1 resections (n=9) | 23 | N/A/N/A | N/A |
Maggiori et al. (15)b | |||
R1 resections (n=37)c | 32 | 40%/6% | 11/2 |
Current studyb | |||
All patients (n=11) | 15 | 30%/20% | 13/1 |
R1 resections (n=10) | 30 | 33%/22% | 13.7/1 |
a11 patients had several combinations of distant metastases and only 16 patients had isolated HM. Survival data is for all 27; bOnly two controlled study comparison, both case-control; cAll patients were R1 resections; dUnreliable data due to short observation time and many censured patients; Abbreviations: PM, peritoneal metastases; HM, hepatic metastases; PCI, peritoneal cancer index