Table 2. Comparison of demographic and clinicopathologic characteristics between patients who developed isolated local recurrence/progression less than versus greater than 9 months following surgery or definitive chemoradiation therapy (CRT).

	All patients (n=18)	<9 months (n=8)	>9 months (n=10)	P
Characteristic
Age: median years [range]	64 [42-72]	60 [45-72]	67 [42-71]	0.51
Gender: No. male [%]	10 [56]	4 [50]	6 [60]	0.67
ECOG: No. 0-1 [%]	17 [94]	7 [88]	10 [100]	0.25
Tumor diameter: median cm [range]	3 [2.0-4.5]	3 [2.5-4.5]	3 [2.0-4.0]	0.48
Grade: No. moderately differentiated [%]	13 [72]	5 [63]	8 [80]	0.41
Resection margin: No. positive [%]	6 [33]	3 [38]	3 [30]	0.74
No. with lymph node involvement [%]	11 [61]	5 [63]	4 [60]	0.91
No. with perineural invasion [%]	10 [56]	5 [63]	5 [50]	0.60
No. with lymphovascular invasion [%]	10 [56]	4 [50]	6 [60]	0.67
Outcome
Median survival (months)	8.8	3.4	11.3	0.02
Median progression-free survival (months)	3.7	3.2	10.6	0.03

ECOG, Eastern Cooperative Oncology Group