Table 3.
Groups | Hepatocyte degeneration | Vascular congestion | Sinusoidal dilatation | Congestion in enlarged sinusoids | Fatty degeneration |
Apoptosis index (AI) |
---|---|---|---|---|---|---|
G1 (control) | 0.43 ± 0.535a | 0.57 ± 0.535ab | 0.29 ± 0.488a | 0.29 ± 0.488a | 0.0 ± 0.0a | 3.57 ± 2.15a |
G2 (control) | 0.43 ± 0.535a | 0.71 ± 0.488abc | 0.86 ± 0.378ab | 0.29 ± 0.488a | 0.0 ± 0.0a | 4.71 ± 1.70a |
G3 (control) | 0.29 ± 0.488a | 0.43 ± 0.535a | 0.71 ± 0.488ab | 0.29 ± 0.488a | 0.0 ± 0.0a | 3.86 ± 1.68a |
G4 (CCI4) | 2.71 ± 0.488c | 0.71 ± 0.488abc | 1.57 ± 0.535c | 0.86 ± 0.378b | 3.00 ± 0.0c | 35.57 ± 6.35d |
G5 (silibinin) | 2.00 ± 0.577b | 1.14 ± 0.69bcd | 1.29 ± 0.756bc | 0.71 ± 0.488ab | 1.86 ± 0.69b | 20.0 ± 3.16c |
G6 (low pollen) | 2.14 ± 0.378b | 1.43 ± 0.535d | 1.29 ± 0.756bc | 0.86 ± 0.378b | 2.14 ± 0.69b | 21.57 ± 4.04c |
G7 (high pollen) | 1.71 ± 0.488b | 1.29 ± 0.488cd | 1.29 ± 0.488bc | 0.71 ± 0.488ab | 1.71 ± 0.756b | 15.86 ± 3.29b |
The histological score was calculated using a scale from 0 to 3, 0: none, 1: mild, 2: moderate, and 3: severe.
aValues are significantly different from G4, G5, G6, and G7 (P < 0.05).
bValues are significantly different from those of controls (G1–G3) (P < 0.05).
cValues are significantly different from those of silibinin (G5) (P < 0.05).
dValues are significantly different from G7 (400 mg pollen/kg B.W.) (P < 0.05).