Table 2.

Hemodynamic and Biochemical Profile Before and After LVAD Unloading

Hemodynamics	Pre-LVAD	Post-LVAD	p-value
Mean BP, mm Hg	79 [74, 86]	89 [81, 99]*	0.0001
HR, beats/min	94 [84, 112]	88 [80, 99]	0.02
RAP, mm Hg	14 [9, 18]	8 [4, 10]	0.0008
PCWP, mm Hg	28 [23, 30]	13 [9, 19]	<0.0001
PASP, mm Hg	55 [44, 64]	32 [26, 41]	<0.0001
PADP, mm Hg	27 [24, 32]	14 [11, 18]	<0.0001
Mean PAP, mm Hg	38 [31, 43]	21 [17, 27]	<0.0001
PVR, Woods units	3.0 [1.9, 4.7]	1.8 [1.2, 2.2]	0.0007
Cardiac index, L/(min· m2)	1.7 [1.5, 2.0]	2.4 [2.1, 2.8]	0.0001
Biochemical
Serum sodium, mEq/L	135 [132, 138]	138 [136, 140]	<0.0001
Serum BUN, mg/dl	28 [20, 38]	20 [15, 29]	0.0001
Serum creatinine, mg/dl	1.3 [1.0, 1.7]	1.1 [0.9, 1.4]	0.02
Serum bilirubin, mg/dl	1.2 [0.7, 1.6]	0.8 [0.5, 1.2]	0.03
Serum hemoglobin, g/dl	12.5 [11, 14]	11.6 [10, 13]	<0.0001
Platelet count, 109/L	182 [144, 236]	207 [152, 288]	0.03

BP= blood pressure; BUN=blood urea nitrogen; HR=heart rate; PADP=pulmonary artery diastolic pressure; PAP=pulmonary artery pressure; PASP=pulmonary artery systolic pressure; PCWP=pulmonary capillary wedge pressure; PVR=pulmonary vascular resistance; RAP=right atrial pressure. Values are expressed as median [25th, 75th percentiles].

^*The post-LVAD blood pressure is an approximate systolic/mean blood pressure due to the continuous-flow of the LVAD.