Table 1.
Characteristics | C4d(+) ABMR (n = 11) | C4d(−) ABMR (n = 5) | TCMR (n = 10) | P value |
---|---|---|---|---|
Gender, male (%) | 2 (18.2) | 4 (80.0) | 9 (90.0) | 0.002 |
Age (years) | 40.18 ± 8.38 | 39.60 ± 12.95 | 38.80 ± 11.74 | 0.957 |
Donor age (years) | 44.00 ± 9.89 | 44.90 ± 11.92 | 41.20 ± 10.84 | 0.771 |
Positive pretransplant PRA (n) | 0 | 0 | 0 | — |
Previous transplant | 0 | 0 | 0 | — |
Cold ischemic time (h) | 8.18 ± 1.40 | 8.40 ± 1.14 | 8.93 ± 1.57 | 0.866 |
Warm ischemic time (min) | 6.36 ± 1.20 | 6.20 ± 1.30 | 6.80 ± 1.31 | 0.623 |
Induction with IL-2R antibody, n (%) | 11 (100) | 5 (100) | 10 (100) | — |
Baseline immunosuppressants | 0.118 | |||
MMF + Tac + Pred | 11 (100) | 5 (100) | 10 (100) | — |
Time of biopsy after Tx (day) | 6.36 ± 5.16 | 3.40 ± 0.89 | 11.50 ± 4.90 | 0.008 |
PRA: panel-reactive antibody; IL: interleukin; MMF: mycophenolate mofetil; Pred: prednisolone; Tac: tacrolimus; Tx: transplantation; ABMR: antibody-mediated rejection; TCMR, T-cell-mediated rejection.