Fig. 1. Effect of SB-657510 (SB) on urotensin II (UII)-induced attachment of monocytes to endothelial cells. After treatment with 100 nM UII for the indicated times in the presence or absence of SB, EA.hy926 cells were incubated with U937 monocytes for 1 h. Representative images and quantitative analysis are shown in top and bottom, respectively. (A) Adhesion assay after UII treatment. Arrow, attached U937 monocyte; scale bar, 100 μm. *p<0.05 vs. 0 h. n=3. (B) Adhesion assay after UII and SB treatment. Arrow, attached U937 monocyte, scale bar, 100 μm. *p<0.05 vs. control (CTL), #p<0.05 vs. vehicle (Veh). n=3.
