Fig. 3. Quetiapine (A) 5 mg/kg, (B) 7 mg/kg or (C) 10 mg/kg, i.p. was injected prior to serotonin (5-HT, 3-4 mg/kg, i.c.v.) administration (after serotonin treatment: control’, A’ (5 mg/kg), B’ (7 mg/kg), C’ (10 mg/kg), i.p.). The score of response in groups (n=15) was measured for 2 min, 3 times, 10 min of interval. Each value is the mean ± S.E. ^*p<0.05, compared with saline treated group.