Table 1.

Association results for change in lutein and MPOD after supplementation with Lutein and Zeaxanthin.

Gene	SNP	Chr.	Position	MAF	Effect allele	Lutein			MPOD
						Beta	SE	p-value	Beta	SE	p-value
RPE65	rs4926339	1	68694879	0.42	A	−0.04	0.016	0.01	0.029	0.014	0.04
ABCG5	rs10179921	2	43921795	0.05	A	0.237	0.23	0.3	−0.023	0.028	0.4
ELOVL2	rs1150561	6	11071833	0.02	A	−0.736	0.361	0.04	−0.045	0.053	0.4
ABCA1	rs1929841	9	106587443	0.16	G	−0.177	0.127	0.16	−0.041	0.016	0.01
FADS1	rs174534	11	61306034	0.38	G	−0.001	0.1	0.99	0.032	0.015	0.03
SCARB1	rs838879	12	123827394	0.22	G	0.011	0.138	0.94	0.004	0.02	0.84
SCARB1	rs11057841	12	123882696	0.09	T	−0.21	0.245	0.39	−0.078	0.033	0.02
SCARB1	rs4379922	12	123917069	0.27	G	0.085	0.109	0.43	0.008	0.013	0.54
BCMO1	rs11645428	16	79816397	0.33	A	0.133	0.115	0.25	−0.01	0.014	0.48
BCMO1	rs6564851	16	79822098	0.46	G	0.036	0.104	0.73	0.009	0.014	0.51
BCMO1	rs6564863	16	79852394	0.43	T	0.04	0.102	0.7	0.001	0.0013	0.96
ALDH3A2	rs8069576	17	19510912	0.47	A	−0.041	0.1	0.68	0.006	0.015	0.688

SNP – single nucleotide polymorphism; Chr. – chromosome; Position – physical position of variants is given according to NCBI Human Genome build 36; MAF – minor allele frequency; beta – betas for change in lutein concentration are not back-transformed; SE – standard error; MPOD – macular pigment optical density; bold – SNPs reaching nominal significance.