Table V.
Clinical characteristics at 3-years for subsets of symptomatic hand OA (n = 963)
| Unclassified∗ | Erosive OA | Generalised hand OA | IPJ and thumb base OA | Thumb base OA | Nodal IPJ OA | Non-nodal IPJ OA | Difference between the groups (ANCOVA) significance | |
|---|---|---|---|---|---|---|---|---|
| AUSCAN Pain (0–20) | ||||||||
| Crude baseline mean score (95% CI) | 6.3 (5.8, 6.8) | 8.0 (6.7, 9.2) | 6.8 (6.2, 7.5) | 6.3 (5.4, 7.2) | 6.6 (6.0, 7.2) | 7.2 (6.2, 8.2) | 6.8 (5.6, 7.9) | P = 0.215 |
| Crude 3-years mean score (95% CI) | 6.2 (5.7, 6.7) | 8.9 (7.4, 10.3) | 7.6 (6.9, 8.4) | 7.5 (6.5, 8.5) | 7.1 (6.5, 7.8) | 8.3 (7.2, 9.4) | 7.2 (5.9, 8.5) | P < 0.001 |
| Adjusted 3-years mean score (95% CI)† | 6.6 (6.1, 7.0) | 8.0 (6.8, 9.2) | 7.7 (7.0, 8.3) | 8.0 (7.1, 8.8) | 7.1 (6.6, 7.7) | 8.0 (7.1, 8.9) | 7.4 (6.3, 8.5) | P = 0.006 |
| AUSCAN Function (0–36) | ||||||||
| Crude baseline mean score (95% CI) | 9.3 (8.4, 10.2) | 13.5 (11.0, 15.9) | 11.1 (9.8, 12.5) | 9.9 (8.1, 11.7) | 10.6 (9.5, 11.8) | 10.8 (8.9, 12.7) | 10.0 (7.8, 12.2) | P = 0.039 |
| Crude 3-years mean score (95% CI) | 9.5 (8.5, 10.4) | 16.5 (13.8, 19.2) | 12.2 (10.7, 13.6) | 11.6 (9.7, 13.5) | 11.5 (10.3, 12.8) | 12.5 (10.5, 14.5) | 10.8 (7.8, 12.2) | P < 0.001 |
| Adjusted 3-years mean score (95% CI)† | 10.6 (10.0, 11.3) | 13.9 (12.1, 15.6) | 11.9 (10.9, 12.9) | 12.6 (11.2, 13.9) | 11.3 (10.5, 12.2) | 12.3 (10.9, 13.6) | 11.4 (9.7, 13.0) | P = 0.007 |
Analysis was completed on CASHA and CASK study participants using mutually exclusive subsets as determined in Fig. 1; Data are marginal means and 95% CI estimated from the ANCOVA model, baseline mean scores in this table differ from those in Table IV as these are for the individuals who were followed-up at 3-years.
Individuals in this sub-group are symptomatic with pain in the last month and may have some radiographic changes, but they do not meet the criteria for any of the hand OA subsets.
Adjusted for baseline score; ANCOVA, Analysis of covariance; Data was missing for the following characteristics: AUSCAN Pain at baseline n = 117 (12.1%), AUSCAN Pain at 3-years n = 156 (16.2%), AUSCAN Function at baseline n = 1078 (11.1%) and AUSCAN Function at 3-years n = 146 (15.2%).