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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Value Health. 2013 Sep-Oct;16(6):10.1016/j.jval.2013.07.006. doi: 10.1016/j.jval.2013.07.006

Figure 2.

Figure 2

State-transition diagram for chronic hepatitis C and liver disease model. The model consists of two components: treatment and natural history. If patients discontinue treatment, or fail to achieve an end-of-treatment response (ETR) or a sustained virologic response (SVR), they enter the natural history component of the model, which consists of 14 health states. These include fibrosis states (F0–F4); decompensated cirrhosis (first year [DC1] and subsequent years [DC+]); hepatocellular carcinoma (HCC); liver transplant (first year [LT] and subsequent years [PLT]; liver-related death (Lv-Death); death from all other causes (not shown here); and SVR status states stratified by fibrosis stage (“SVR, F0–F3” and “SVR, F4”).

Y= Yes; N=No.

*For clarity, two decompensated states--DC1 and DC+ are shown as one state, i.e. DC.