Table 1.
Characteristics | N = 403 |
---|---|
Gender – no. (%) | |
Male | 268 (67) |
Female | 135 (33) |
Age – years | |
Mean | 52.7 |
Standard Deviation | 7.7 |
Range | 26–74 |
Race – no. (%) | |
Black | 49 (12) |
Non-Black | 354 (88) |
Prior Treatment Experience – no. (%)* | |
Non-Responders | 144 (36) |
Relapsers | 259 (64) |
Baseline METAVIR Score – no. (%)† | |
F0 – no fibrosis | 18 (4) |
F1 – portal fibrosis without septa | 200 (50) |
F2 – portal fibrosis with few septa | 79 (20) |
F3 – numerous septa without cirrhosis | 29 (7) |
F4 – cirrhosis | 49 (12) |
Missing‡ | 28 (7) |
Prior nonresponders had a decrease in plasma HCV-RNA of at least 2-log10 by week 12 of prior therapy but with detectable HCV-RNA throughout the course of therapy. Prior relapsers had undetectable HCV-RNA at end of prior therapy without subsequent attainment of a sustained virologic response.
A central pathologist determined fibrosis score. Twenty-eight patients had missing data.
Patients with missing METAVIR score were not included in the model.