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. Author manuscript; available in PMC: 2013 Nov 7.
Published in final edited form as: Neuropharmacology. 2009 Feb 5;56(0):10.1016/j.neuropharm.2009.01.020. doi: 10.1016/j.neuropharm.2009.01.020

Figure 14. Cylinder Test for PG01037.

Figure 14

Unilaterally lesioned rats were tested for the percentage of forelimb preference (either right (R), left (L) or both (B) forelimbs) using the cylinder test. Animals were injected with either vehicle (control) or L-dopa/benserazide (L-dopa) (8 mg/kg each) in the absence or presence of PG01037 (L-dopa/PG01037). Animals were injected with L-dopa and test drug or vehicle simultaneously, then evaluated at 12 minutes (A) and 20 minutes (B) post injection. It was not possible to evaluate the animals at 20 minutes post drug administration when animals were given L-dopa/benserazide in the absence of PG01037 due to the intensity of the abnormal involuntary movements. Data are plotted as the mean values ± S.E.M. for seven animals (n = 7).