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. Author manuscript; available in PMC: 2013 Nov 7.
Published in final edited form as: Neuropharmacology. 2009 Feb 5;56(0):10.1016/j.neuropharm.2009.01.020. doi: 10.1016/j.neuropharm.2009.01.020

Figure 8. Effect of thirty five minute post-treatment of PG01037 on the L-dopa dependent individual AIMs in lesioned rats.

Figure 8

A scatter gram of the summation of locomotor activity (Loco), axial dystonic movements (Axial), forelimb movement (Forelimb) and orolingual movements (Oro) for n = 12 animals is shown. Open circles (○) designate vehicle control values and solid circles (●) designate animals administered PG01037 35 minutes after the L-dopa administration and then scored at 50, 70, 90 and 100 minutes post L-dopa treatment. There was a 66.6%, 69.5%, 61.9% and 55.0% reduction in the locomotor, axial, forelimb and orolingual movements, respectively. The overall mean reduction in total AIMs score was 64.5 ± 35.1 (S.E.M.).