Figure 1.
MO ICS data showing the results from Experiments 1, 2 and 3. Experiment 1: Male and female whole-blood MOs incubated concurrently with 50 ng/mL LPS and 0–1000 pM OT, analyzed via FACS. Experiment 2: Male and female whole-blood MOs incubated with 50 ng/mL LPS and either concurrently or following a 30- or 60-minute pre-incubation with 0–1000 pM OT, analyzed via FACS. Experiment 3: Male and female isolated PBMCs incubated with 50 ng/mL LPS following a 30-minute pre-incubation with 0–1000 nM OT, analyzed via FACS. PI = pre-incubation, CI = concurrent incubation, n = number of participants per condition. Data are expressed as percentage of CD14+ cells that also stain IL-6+.