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. 2013 Aug 16;68(12):2907–2914. doi: 10.1093/jac/dkt295

Table 4.

Summary of quinolone resistance mutations and qnr genes found in isolates with ciprofloxacin MICs ≥0.12 mg/L

No. Ciprofloxacin MIC (mg/L) ESBL qnrB qnrS gyrA mutation parC mutation
50 0.12 no no no nil nil
61 0.12 no no no nil nil
125 0.12 no no no nil nil
172 0.12 no no no nil nil
68 0.25 no no no nil nil
93 0.25 no no no nil nil
134 0.25 no no no nil nil
46 0.25 no yes no nil nil
55 0.5 no no no nil nil
23 0.5 no yes no nil nil
34 0.5 no no no TCC→TAC, Ser83→Tyr nil
191 1 no no no nil nil
189 1 no no yes nil nil
154 1 no no no TCC→TAC, Ser83→Tyr nil
208 4 no yes no TCC→TAC, Ser83→Tyr nil
103 16 no no yes TCC→TTC, Ser83→Phe nil
128 16 no yes no TCC→TTC, Ser83→Phe nil
44 16 yes no no TCC→TTC, Ser83→Phe nil
35 32 no no no TCC→ATC, Ser83→Phe AGC→ATC, Ser80→Ile
9 64 yes no yes TCC→TTC, Ser83→Phe nil
45 64 no yes no TCC→ATC, Ser83→Phe GAA→AAA, Glu84→Lys
21 64 yes no no TCC→ATC, Ser83→Phe AGC→ATC, Ser80→Ile
173 64 no no no TCC→ATC, Ser83→Phe AGC→ATC, Ser80→Ile
104 >128 yes yes no TCC→ATC, Ser83→Phe AGC→ATC, Ser80→Ile