Table 2.
Comparison of Quality of Life Scores Between HIV-Infected Children Categorized by Treatment Arms and Healthy Children
| |
|
Baseline |
Week 144 |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Healthy children | All HIV-infected children | pa | Early | pa | Deferred | pa | All HIV-infected children | pa | Early | pa | Deferred | pa | |
| Health perception | 79.9 (13.2) | 70.5 (17.4) | <0.01 | 69.6 (16.5) | <0.01 | 71.2 (18.2) | <0.01 | 77.2 (12.8) | <0.01 | 77.6 (12.1)b | <0.01 | 76.9 (13.5)b | <0.01 |
| Physical resilience | 77.3 (12.6) | 70.4 (13.1) | <0.01 | 69.2 (13.2) | <0.01 | 71.6 (13.1) | <0.01 | 74.6 (12.1) | <0.01 | 75.8 (11.7)b | <0.01 | 73.5 (12.4) | <0.01 |
| Physical functioning | 90.4 (13.7) | 87.2 (12.8) | <0.01 | 86.8 (12.5) | <0.01 | 87.7 (13.1) | <0.01 | 93.7 (11.4) | <0.01 | 94.1 (11.2)b | <0.01 | 93.4 (11.7)b | 0.03 |
| Psychosocial well-being | 84.7 (11.7) | 78.7 (15.8) | <0.01 | 77.4 (17.4) | <0.01 | 79.6 (14.4) | 0.01 | 83.2 (14.9) | 0.68 | 84.2 (13.6)b | 0.87 | 82.7 (14.7) | 0.41 |
| Social functioning | 98.4 (4.8) | 96.5 (8.1) | 0.01 | 96.3 (8.6) | 0.03 | 96.7 (7.7) | 0.03 | 97.3 (7.3) | 0.24 | 97.4 (8.1) | 0.77 | 97.4 (6.4) | 0.10 |
| Health care utilization | 99.1 (3.1) | 92.6 (7.1) | <0.01 | 93.0 (7.0) | <0.01 | 92.0 (7.4) | <0.01 | 96.1 (4.8) | <0.01 | 96.2 (4.8)b | <0.01 | 96.1 (4.9)b | <0.01 |
| Symptoms | 96.4 (4.4) | 90.5 (7.7) | <0.01 | 91.1 (7.2) | <0.01 | 89.8 (8.3) | <0.01 | 94.3 (6.1) | 0.01 | 95.0 (6.0)b | 0.01 | 93.6 (6.3)b | <0.01 |
Data are presented as mean (SD). ap values were compared with QOL scores in age-matched healthy children. bWhen compared within this arm, the QOL scores in this domain increased significantly compared to baseline scores (p<0.01).