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. 2013 Sep 12;6(6):1316–1324. doi: 10.1242/dmm.011940

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© 2013. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 2. — Motor activity was assessed in Sprague-Dawley rats (similar data obtained with CD-1 mice) by number of beam breaks. When rats pass through infrared beams it is recorded as a beam break. Two separate vehicle control groups reveal similar activity counts across the 60 minutes. Amphetamine (1.0 mg/kg) and haloperidol (0.5 mg/kg) were used to provide a positive and negative control, respectively, to further validate the assay. These drugs are common controls that are expected to increase (amphetamine) or decrease (haloperidol) motor activity. Data were obtained from WIL Research validation efforts.