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. 2013 Aug 29;6(6):1378–1387. doi: 10.1242/dmm.013482

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© 2013. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 6. — Regulation of Pdgfrβ expression by superoxide anions. (A) PDGFRβ protein (left) and mRNA (right) expression in MLFs exposed to tempol. Relative Pdgfrβ transcript levels are represented as means ± s.e.m. of three separate experiments. (B) Superoxide anion levels in MLFs quantified by electron paramagnetic resonance spectroscopy (EPR). Results are represented as means ± s.e.m. of six independent measurements. AU, arbitrary units. (C) PDGFRβ expression in MLFs exposed to phorbol 12-myristate 13-acetate (PMA) ± tempol. Left panel: representative western blot. Right panel: PDGFRβ levels quantified by densitometry. Results are represented as means ± s.e.m. of three separate experiments. *P<0.05.