Table 3.
Multivariate analysis of body weight gain during treatment and treatment outcome (N = 439)
| Weight gain from baseline | Underweight (BMI < 18.5) | Not underweight (BMI ≥ 18.5) | ||||
|---|---|---|---|---|---|---|
| Cured | Poor outcome | Adjusted OR (95% CI)* | Cured | Poor outcome | aOR* (95% CI) | |
| Month 1 | ||||||
| > 5% | 42 (73.7) | 15 (26.3) | 0.9 (0.4, 1.9) | 18 (78.3) | 5 (21.7) | 1.1 (0.4, 3.2) |
| ≤ 5% | 104 (72.7) | 39 (27.3) | ref | 102 (76.7) | 31 (23.3) | ref |
| Month 2 | ||||||
| > 5% | 56 (76.7) | 17 (23.3) | 1.2 (0.6, 2.5) | 32 (74.4) | 11 (25.6) | 0.6 (0.2, 1.3) |
| ≤ 5% | 92 (70.2) | 39 (29.8) | ref | 96 (83.5) | 19 (16.5) | ref |
| Month 3 | ||||||
| > 5% | 71 (79.8) | 18 (20.2) | 2.1 (1.1, 4.4) | 38 (73.1) | 14 (26.9) | 0.6 (0.3, 1.3) |
| ≤ 5% | 71 (68.3) | 33 (31.7) | ref | 82 (82.0) | 18 (18.0) | ref |
| Month 4 | ||||||
| > 5% | 75 (79.8) | 19 (20.2) | 2.8 (1.3, 6.2) | 44 (80.0) | 11 (20.0) | 1.1 (0.5, 2.5) |
| ≤ 5% | 57 (64.8) | 31 (35.2) | ref | 77 (78.6) | 21 (21.4) | ref |
| Month 5 | ||||||
| > 5% | 78 (80.4) | 19 (19.6) | 2.8 (1.3, 5.9) | 48 (75.0) | 16 (25.0) | 0.6 (0.3, 1.4) |
| ≤ 5% | 51 (63.0) | 30 (37.0) | ref | 68 (82.9) | 14 (17.1) | ref |
| Month 6 | ||||||
| > 5% | 80 (78.4) | 22 (21.6) | 2.3 (1.1, 5.3) | 51 (81.0) | 12 (19.1) | 0.7 (0.3, 1.7) |
| ≤ 5% | 47 (67.1) | 23 (32.9) | ref | 68 (86.1) | 11 (13.9) | ref |
*
Adjusted for age, sex, culture conversion, and any treatment interruption.
BMI = body mass index; OR = odds ratio; CI = confidence interval; aOR = adjusted odds ratio.