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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Curr Opin Neurobiol. 2013 May 13;23(3):330–338. doi: 10.1016/j.conb.2013.04.005

Figure 2.

Figure 2

Sex determination and differentiation of the nervous system in fruit flies and mice. Sex determination in fruit flies is cell-autonomous, and sexually dimorphic behaviors are controlled by neurons expressing sex-specific splice forms of Dsx and Fru. In mice, the sex-determination pathway directs the differentiation of the bipotential gonad into ovaries or testes. Gonadal sex steroids and their cognate receptors control the sexual differentiation of nervous system and the expression of sex-typical behaviors in the adult.