Table 3.
1- and 5-year survival and mortality rate ratios (MRRs) after lung cancer diagnosis by level of comorbidity and study period in the Central Denmark Region 2000–2011
| Charlson score | 0 | 1–2 | 3+ |
|---|---|---|---|
| 2000–2002 | |||
| Number of patients | 1143 | 792 | 234 |
| Median age | 67 years | 71 years | 71 years |
| 1-year | |||
| Survival | 33% (31%–36%) | 29% (26%–32%) | 25% (20%–31%) |
| MRR | 1 (reference) | 1.16 (1.04–1.30) | 1.31 (1.11–1.54) |
| Adjusted MRR* | 1 (reference) | 1.10 (0.98–1.23) | 1.23 (1.05–1.46) |
| 5-year | |||
| Survival | 12% (10%–14%) | 9% (7%–11%) | 6% (4%–10%) |
| MRR | 1 (reference) | 1.14 (1.04–1.26) | 1.28 (1.11–1.49) |
| Adjusted MRR* | 1 (reference) | 1.09 (0.99–1.20) | 1.21 (1.04–1.40) |
| 2003–2005 | |||
| Number of patients | 1096 | 780 | 312 |
| Median age | 67 years | 71 years | 72 years |
| 1-year | |||
| Survival | 35% (32%–38%) | 34% (31%–38%) | 28% (23%–33%) |
| MRR | 1 (reference) | 1.06 (0.94–1.18) | 1.22 (1.05–1.42) |
| Adjusted MRR* | 1 (reference) | 0.97 (0.87–1.09) | 1.12 (0.96–1.30) |
| 5-year | |||
| Survival | 12% (10%–14%) | 9% (7%–11%) | 8% (5%–11%) |
| MRR | 1 (reference) | 1.06 (0.96–1.17) | 1.17 (1.02–1.33) |
| Adjusted MRR* | 1 (reference) | 0.99 (0.90–1.10) | 1.10 (0.96–1.26) |
| 2006–2008 | |||
| Number of patients | 1240 | 893 | 331 |
| Median age | 68 years | 72 years | 73 years |
| 1-year | |||
| Survival | 36% (33%–39%) | 33% (30%–36%) | 31% (26%–36%) |
| MRR | 1 (reference) | 1.10 (0.99–1.22) | 1.21 (1.04–1.40) |
| Adjusted MRR* | 1 (reference) | 1.03 (0.93–1.15) | 1.15 (0.99–1.33) |
| 5-year | |||
| Survival | 14% (12%–16%)† | 12% (10%–14%)† | 6% (4%–9%)† |
| MRR | 1 (reference) | 1.08 (0.98–1.18)† | 1.27 (1.12–1.44)† |
| Adjusted MRR* | 1 (reference) | 1.02 (0.93–1.12)† | 1.22 (1.07–1.38)† |
| 2009–2011 | |||
| Number of patients | 1237 | 925 | 386 |
| Median age | 68 years | 73 years | 75 years |
| 1-year | |||
| Survival | 41% (38%–44%) | 37% (33%–40%) | 28% (23%–33%) |
| MRR | 1 (reference) | 1.15 (1.03–1.29) | 1.55 (1.35–1.79) |
| Adjusted MRR* | 1 (reference) | 1.08 (0.96–1.21) | 1.35 (1.17–1.56) |
| 5-year | |||
| Survival | 15% (13%–18%)† | 13% (11%–15%)† | 7% (5%–11%)† |
| MRR | 1 (reference) | 1.11 (1.01–1.22)† | 1.40 (1.24–1.58)† |
| Adjusted MRR* | 1 (reference) | 1.04 (0.95–1.15)† | 1.26 (1.11–1.42)† |
Notes:
*
Adjusted for differences in age and sex;
†
estimated values.