Table 2.
Overall survival and mortality rate ratios after colon and rectal cancer according to diagnostic calendar periods in the Central Region of Denmark 2000–2011
| Year of diagnosis
|
2009–2011 | |||
|---|---|---|---|---|
| 2000–2002 | 2003–2005 | 2006–2008 | ||
| Colon cancer | ||||
| Number of patients | 1292 | 1347 | 1528 | 1610 |
| 1-year | ||||
| Survival | 68% (65%–70%) | 70% (67%–72%) | 71% (69%–73%) | 73% (71%–75%) |
| MRR crude | 1 (reference) | 0.95 (0.83–1.08) | 0.87 (0.76–1.00) | 0.81 (0.71–0.93) |
| MRR adjusteda | 1 (reference) | 0.87 (0.76–0.99) | 0.79 (0.69–0.91) | 0.74 (0.64–0.85) |
| 5-year | ||||
| Survival | 39% (37%–42%) | 44% (41%–47%) | 45% (43%–48%)b | 46% (43%–48%)b |
| MRR crude | 1 (reference) | 0.89 (0.80–0.98) | 0.86 (0.78–0.95)b | 0.83 (0.76–0.92)b |
| MRR adjusteda | 1 (reference) | 0.83 (0.75–0.92) | 0.79 (0.72–0.87)b | 0.76 (0.69–0.84)b |
| Rectal cancer | ||||
| Number of patients | 716 | 635 | 760 | 853 |
| 1-year | ||||
| Survival | 77% (74%–80%) | 77% (73%–80%) | 80% (77%–82%) | 82% (79%–85%) |
| MRR crude | 1 (reference) | 1.03 (0.83–1.29) | 0.87 (0.70–1.09) | 0.76 (0.61–0.96) |
| MRR adjusteda | 1 (reference) | 1.02 (0.82–1.28) | 0.85 (0.68–1.05) | 0.70 (0.56–0.88) |
| 5-year | ||||
| Survival | 46% (42%–50%) | 50% (46%–54%) | 49% (45%–52%)b | 51% (48%–55%)b |
| MRR crude | 1 (reference) | 0.92 (0.79–1.06) | 0.92 (0.80–1.06)b | 0.84 (0.73–0.97)b |
| MRR adjusteda | 1 (reference) | 0.90 (0.77–1.04) | 0.91 (0.79–1.05)b | 0.80 (0.70–0.93)b |
Notes: Figures in brackets represent 95% confidence intervals;
a
MRRs in different calendar periods using 2000–2002 as reference, adjusted for changes over time in age, sex, and comorbidity;
b
predicted values.
Abbreviation: MMR, mortality rate ratio.