Table 4.
One-year and 5-year survival and relative mortality after rectal cancer according to comorbidity level for each diagnostic period in the Central Region of Denmark 2000–2011
| Charlson score
|
|||
|---|---|---|---|
| 0 | 1–2 | 3+ | |
| 2000–2002 | |||
| Number of patients | 512 | 163 | 41 |
| 1-year | |||
| Survival (%) | 81% (77%–84%) | 69% (62%–76%) | 56% (40%–70%) |
| MRR crude | 1 (reference) | 1.76 (1.25–2.47) | 2.73 (1.65–4.52) |
| MRR adjusteda | 1 (reference) | 1.46 (1.03–2.06) | 2.21 (1.33–3.68) |
| 5-year | |||
| Survival (%) | 51% (47%–56%) | 36% (29%–44%) | 17% (8%–30%) |
| MRR crude | 1 (reference) | 1.58 (1.25–1.98) | 2.50 (1.74–3.57) |
| MRR adjusteda | 1 (reference) | 1.37 (1.09–1.73) | 2.00 (1.39–2.88) |
| 2003–2005 | |||
| Number of patients | 427 | 167 | 41 |
| 1-year | |||
| Survival (%) | 81% (77%–84%) | 71% (63%–77%) | 56% (40%–70%) |
| MRR crude | 1 (reference) | 1.64 (1.15–2.34) | 2.74 (1.64–4.56) |
| MRR adjusteda | 1 (reference) | 1.25 (0.87–1.80) | 2.40 (1.43–4.02) |
| 5-year | |||
| Survival (%) | 56% (51%–60%) | 41% (33%–48%) | 24% (13%–38%) |
| MRR crude | 1 (reference) | 1.56 (1.22–1.99) | 2.46 (1.68–3.59) |
| MRR adjusteda | 1 (reference) | 1.27 (0.99–1.64) | 2.20 (1.50–3.23) |
| 2006–2008 | |||
| Number of patients | 499 | 194 | 67 |
| 1-year | |||
| Survival (%) | 84% (80%–87%) | 76% (70%–82%) | 61% (48%–72%) |
| MRR crude | 1 (reference) | 1.52 (1.06–2.19) | 2.67 (1.72–4.15) |
| MRR adjusteda | 1 (reference) | 1.13 (0.77–1.64) | 1.95 (1.24–3.07) |
| 5-year | |||
| Survival (%) | 54% (50%–58%)b | 43% (36%–50%)b | 21% (11%–33%)b |
| MRR crude | 1 (reference) | 1.40 (1.11–1.76)b | 2.33 (1.71–3.17)b |
| MRR adjusteda | 1 (reference) | 1.13 (0.89–1.44)b | 1.87 (1.36–2.57)b |
| 2009–2011 | |||
| Number of patients | 567 | 221 | 65 |
| 1-year | |||
| Survival (%) | 87% (83%–89%) | 78% (71%–83%) | 60% (46%–71%) |
| MRR crude | 1 (reference) | 1.82 (1.25–2.67) | 3.96 (2.48–6.33) |
| MRR adjusteda | 1 (reference) | 1.51 (1.02–2.24) | 3.09 (1.91–5.00) |
| 5-year | |||
| Survival (%) | 58% (53%–62%)b | 44% (37%–51%)b | 22% (12%–35%)b |
| MRR crude | 1 (reference) | 1.55 (1.24–1.93)b | 2.67 (1.94–3.66)b |
| MRR adjusteda | 1 (reference) | 1.33 (1.05–1.67)b | 2.24 (1.62–3.10)b |
Notes: Figures in brackets represent 95% confidence intervals;
a
MRRs according to comorbidity level with Charlson score 0 as reference, adjusted for age and sex;
b
predicted estimates.
Abbreviation: MMR, mortality rate ratio.