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. 2013 Nov 7;9(11):e1003323. doi: 10.1371/journal.pcbi.1003323

Figure 5. Interactions associated with genes identified in MyD88-knockout and TRIF-knockout response.

Figure 5

Genes predicted to be part of the optimal sub-network in either the MyD88-knockout or the TRIF-knockout samples. A. Sub-network associated with Git1 which has the highest flow in the MyD88-knockout sample. B.Cry1, a component of the circadian complex and its associated network. C. A sub-network identified for the TRIF-knockout DCs showing the role of MyD88, Nfκb, the cytokines, Jak-Stat pathway and finally Socs1 induction. Edge and node colors indicate relative flow with darker colors signifying greater flow.