Table 5. Components of the optimal sub-network predicted by the proposed method and ResponseNet.

Method	Predicted Genes	Predicted Edges	Intermediate regulators in network	Edges to Intermediate regulators	Amit et. al regulators predicted	Chevrier et al. regulators predicted	Chevrier et al. TLR targets predicted#	KEGG pathways with predicted paths (maximum length*)
ResponseNet	848	1080	49	147	39.2%	53.5%	39.2%	0 (3 edges)
This method	1224	2242	154	1179	49.6%	69.8%	54.9%	13 (7 edges)

^#one gene with 0.05<p<0.1.

^*length indicates the maximum number of consecutive directed edges identified in the pathway.