Table 5. List of differentially enriched pathways during nutrient shift.
| Pathway | p-value | Genes associated |
|---|---|---|
| Carbohydrates Biosynthesis | 1.04E-07 | CD0118, CD0886, CD2318, cooS, eno, fbp, fchA, fhs, folD, gapA, gapB, glgA, glgC, gpmI, pgi, pgk, pmi, pyc, pykF, rkpK, tpiA |
| Sugars Biosynthesis | 3.21E-07 | CD0118, CD0886, cooS, eno, fbp, fchA, fhs, folD, gapA, gapB, gpmI, pgi, pgk, pmi, pyc, pykF, rkpK, tpiA |
| Gluconeogenesis | 8.20E-07 | CD0118, cooS, eno, fbp, fchA, fhs, folD, gapA, gapB, gpmI, pgi, pgk, pyc, pykF, tpiA |
| Generation of Precursor Metabolites and Energy | 1.01E-05 | abfD, abfH, abfT, adhE, adhE, bcd2, buk, cat1, CD0118, CD0715, CD2379, crt2, ctfB, eno, fbp, gapA, gapB, gpmI, hydA, pfkA, pgi, pgk, plfB, ptb, pykF, rpe, rpiB1, rpiB2, thlA1, tkt, tkt', tpiA |
| Adenosine nucleotides de novo biosynthesis | 4.81E-05 | adk, atpA, atpB, atpC, atpD, atpF, atpG, atpH, atpI, ntpA, ntpB, ntpC, ntpD, ntpE, ntpK, purA |
| Fermentation | 1.82E-04 | abfD, abfH, abfT, adhE, adhE, bcd2, buk, cat1, CD0118, CD0715, CD2379, crt2, ctfB, eno, gapA, gapB, gpmI, pgi, pgk, plfB, ptb, pykF, rpe, thlA1 |
| Superpathway of glycolysis and Entner-Doudoroff | 2.49E-04 | eno, fbp, gapA, gapB, gpmI, pfkA, pgi, pgk, pykF, tpiA |
| Amines and Polyamines Degradation | 9.96E-04 | abfD, abfH, abfT, bcd2, CD1585, eutB, eutC, gabT, gluD, nanA, nanE, sucD |
| Purine Nucleotide Biosynthesis | 0.001257477 | adk, atpA, atpB, atpC, atpD, atpF, atpG, atpH, atpI, CD0489, hpt, iunH, ntpA, ntpB, ntpC, ntpD, ntpE, ntpK, purA, pyrH, pyrR, upp, xpt |
| Aspartate superpathway | 0.002091068 | aspD, CD1339, CD2382, CD2828, metE, nadA, nadB, nadC |
| C1 Compounds Utilization and Assimilation | 0.002151781 | CD0118, cooS, fchA, fhs, folD, plfB |
| 4-Aminobutyrate Degradation | 0.002258078 | abfD, abfH, abfT, bcd2, gabT, gluD, sucD |
| Pyruvate Fermentation | 0.004278705 | adhE, adhE, bcd2, buk, cat1, CD0118, CD0715, CD2379, crt2, ctfB, plfB, ptb, thlA1 |
| Reductive acetyl coenzyme A pathway | 0.005518962 | cooS, fchA, fhs, folD |
| Heterolactic fermentation | 0.005744886 | adhE, adhE, eno, gapA, gapB, gpmI, pgi, pgk, pykF, rpe |
| 4-aminobutyrate degradation | 0.006648169 | abfD, abfH, abfT, bcd2, gabT, gluD |
| Folate transformations | 0.006927081 | CD3456, fchA, fhs, folD, glyA |
| Methionine Biosynthesis | 0.007449931 | aspD, CD1339, CD2382, CD2828, dapG, hom2, lysC, malY, metE |
| Purine Nucleotide de novo Biosynthesis | 0.009883003 | adk, atpA, atpB, atpC, atpD, atpF, atpG, atpH, atpI, CD0489, ntpA, ntpB, ntpC, ntpD, ntpE, ntpK, purA |
| Degradation/Utilization/Assimilation | 0.012817157 | abfD, abfH, abfT, adhE, adhE, aspD, bcd2, cat1, CD0118, CD0723, CD1339, CD1585, CD2318, CD2382, CD2819, CD2828, CD3477, cooS, crt2, ctfB, eutB, eutC, fchA, fhs, folD, fruK, gabT, garR, glgP, glpK1, glsA, gluD, glyA, grdC, grdD, grdE, gutD, mdeA, nanA, nanE, pgmB, phnA, plfB, pmi, prdA, prdF, rluB, sucD, thlA1 |
Genes in bold were also found to be differentially expressed in our previous proteomics study.