Table 1.

Clinical and biochemical characteristics of women with ICP and women with normal pregnancies.

	Groups studied
	Normal pregnancies	ICP (low pruritus score)	ICP (high pruritus score)
Number of subjects	38	9	23
Age in years (range)	27 (23–39)	31 (24–39)	27 (21–33)
Number of pregnancies (n)	1.8	1.9	2.3
History of ICP (n)	0	5	5
Familiar history of ICP (n)	0	5	5
Total bilirubin (mg/mL)	0.40 ± 0.02	0.40 ± 0.03	0.83 ± 0.08*
AST (IU/L)	21.0 ± 1.5	21.0 ± 3.0	92.0 ± 13.2**
ALT (IU/L)	14.4 ± 0.8	17.0 ± 2.7	128 ± 25**
ALP (IU/L)	313 ± 20	282 ± 56	674 ± 50**
γ-GT (IU/L)	38 ± 9	36 ± 11	33 ± 3
5′NT (IU/L)	7.8 ± 1.9	7.2 ± 2.4	7.9 ± 2.6

Results are expressed as means ± SEM. For total bilirubin, the normal range is up to 1.1 mg/dL. The normal ranges for AST, ALT, and ALP are 12–31, 12–40, and 90–240 IU/L, respectively. For γ-GT and 5′NT, the normal ranges are up to 40 and 9.7 IU/L, respectively.

^∗ P < 0.05 and ^∗∗ P < 0.01 compared with normal pregnancies.