Skip to main content
. 2012 Aug 1;2012:496489. doi: 10.6064/2012/496489

Table 2.

Comparison of TSBA levels and serum bile acid profiles in all of the groups studied.

Normocholanaemic pregnant women (n = 23) AHP (n = 15) ICP low pruritus score (n = 9) ICP high pruritus score (n = 23) ICP high pruritus score treated with UDCA (n = 23)
TSBA (μM) 5.8 ± 0.7 19.4 ± 2.0§§ 24.2 ± 8.3 54.9 ± 12.2§§ 47.6 ± 11.9§§
UDCA (μM) 3.1 ± 0.7 10.8 ± 1.4§§ 1.1 ± 0.5 5.2 ± 2.8 28.3 ± 6.3§§,a
LCA (μM) 0.34 ± 0.06 0.60 ± 0.28 6.5 ± 3.6§ 20.3 ± 5.6§§ 2.2 ± 1.0∗,a
CDCA (μM) 0.75 ± 0.24 1.3 ± 0.7 1.8 ± 1.0 10.4 ± 4.0∗∗ 8.8 ± 5.6
CA (μM) 0.40 ± 0.17 1.1 ± 0.5 8.8 ± 5.2∗∗ 7.1 ± 2.3§ 5.7 ± 1.9§
DCA (μM) 1.9 ± 0.6 5.6 ± 1.6§ 6.0 ± 4.3 12.0 ± 4.6§ 2.7 ± 1.3§,b
CA/CDCA 1.8 ± 0.9 5.5 ± 2.7 7.7 ± 3.9 18.5 ± 10.9 13.7 ± 7.5
UDCA/LCA ratio 11.1 ± 2.9 41.5 ± 7.5§ 0.65 ± 0.23§ 0.59 ± 1.4§§ 79.9 ± 28.8∗∗,a

Results are expressed as means ± SEM. Bile acids are expressed in their free, glycine, and taurine forms. P < 0.05∗∗ P < 0.01, § P < 0.001 and §§ P < 0.0001, with respect to normocholanaemic pregnant women. a P < 0.0001 and b P < 0.05 with respect to ICP high pruritus score.