Table II.

Overall scores and the five subscale scores of the GSRS after 4 and 8 weeks of treatment with a PPI alone or a PPI combined with rikkunshito.

Subscale score	PPI group (A)			PPI + rikkunshito group (B)
	Baseline	4 weeks	8 weeks	Baseline	4 weeks	8 weeks
Reflux syndrome	1.50±0.61	1.40±0.65	1.30±0.45	1.63±0.64	1.06±0.18	1.13±0.35
Abdominal pain	2.20±0.51	1.13±0.18	1.27±0.37	2.63±1.13	1.42±0.50	1.08±0.15a
Indigestion syndrome	2.40±0.86	1.45±0.45	1.75±0.74	2.06±0.98	1.75±1.03	1.47±0.49
Diarrhoea syndrome	2.40±1.21	1.27±0.37	1.25±0.50	1.67±0.71	1.38±0.58	1.38±0.45
Constipation syndrome	3.27±1.40	2.40±1.67	3.08±1.60	2.75±1.38	2.67±1.55	2.50±1.47
Overall scores	2.35±0.79	1.53±0.56	1.73±0.66	2.15±0.69	1.65±0.58a	1.51±0.35b

^aP<0.05,

^bP<0.01 vs. baseline.

GSRS, Gastrointestinal Symptom Rating Scale; PPI, proton pump inhibitor.