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. 2013 Nov 7;8(11):e78853. doi: 10.1371/journal.pone.0078853

Figure 10. Role of specific cis-regulatory elements in the minimal region of the SLC19A2 and SLC19A3 promoters in mediating the effect of chronic exposure to NNK.

Figure 10

The mutated NNK-responsive minimal region of the SLC19A2 (A) and SLC19A3 (B) promoters in pGL3-Basic were transiently transfected into 266-6 cells and the luciferase assays was determined. Data are reported as relative firefly luciferase activity normalized to Renilla luciferase activity and represent mean ± SE of at least three independent experiments. *P<0.01.