Figure 1. Schematic illustration of the structural domains and features of murine ICK, MAK and MOK protein kinases.

Although ICK, MAK and MOK protein kinases are very similar in their N-terminal catalytic domains, they differ markedly in the structural organization and features in their C-terminal non-catalytic domains. Note that the antigen peptides for ICK, MAK, and MOK proteins are all located at the C-terminal domain by design so as to ensure the antibody specificity.