Table 2. Seroconversion rates following varying doses of purified inactivated EV71.

		Day 28	Day 56
Group	Dose	% seroconverted (n)	% seroconverted (n)
1	Alum control	0 (0/10)	0 (0/10)
2	0.12 µg EV71+Alum	10 (1/10)	50 (5/10)
3	0.6 µg EV71+Alum	20 (2/10)	90 (9/10)
4	3 µg EV71+Alum	70 (7/10)	100 (10/10)
5	9 µg EV71+Alum	40 (4/10)	100 (10/10)
6	15 µg EV71+Alum	80 (8/10)	100 (10/10)

BALB/c mice were immunized with purified inactivated EV71 virus with Alhydrogel, at 28 days and 56 days post primary immunization. Seroconversion is defined as a neutralizing antibody titre of ≥128.