Sweet taste receptors T1R2 and T1R3 are expressed constitutively throughout adipogenesis and in adipose tissues.
A, T1R2 and T1R3 expression throughout 8 days of adipogenesis in 3T3-L1 cells. B, T1R2 and T1R3 expression over 12 days of adipogenesis in eMSCs. C, the indicated tissues were collected from control and 13–15-week-old female db/db mice maintained on a chow diet, and expression of T1R3 mRNA was evaluated by quantitative PCR. Data are expressed as mean ± S.D. (error bars) with n = 4–6/tissue. Analysis by two-way analysis of variance indicates a significant effect of genotype (p < 0.05). gWat, gonadal white adipose tissue; iWAT, inguinal white adipose tissue; pWAT, perirenal white adipose tissue.