Skip to main content
. 2013 Sep 30;288(45):32563–32573. doi: 10.1074/jbc.M113.483750

FIGURE 4.

FIGURE 4.

Myeloid Sphk is not critical for inflammatory responses in vivo. A and B, survival curves of Sphk1−/− and Sphk1+/+ mice (A), Sphk1flox/− Sphk2flox/− LysM-Cre+ and Sphk1flox/− Sphkflox/− LysM-Cre− littermate (B) mice after the injection of LPS (30 mg/kg intraperitoneally). The number of mice in each group is indicated. C, plasma levels of cytokines 8 h after the injection of LPS (30 mg/kg intraperitoneally). The number of mice in each group is indicated. D, total macrophage numbers in peritoneal lavage samples quantified 4 days after injection of 2 ml of 3% thioglycolate (n = 3). Data represent mean ± S.D. (error bars).