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. 2013 Jul 23;12(11):3123–3134. doi: 10.1074/mcp.M113.028134

Table I. Top 50 phospholipid-associated protein pairings as determined by composite correlation score (from 2701 scored pairs ranging from 2.87 to −1.47).

Rank Protein A Protein B Correlation score
Gel filtration Anion exchange IEF Comp.a
1 Fibrinogen β chain Fibrinogen γ chain 0.95 0.97 0.95 2.87
2 Fibrinogen α chain Fibrinogen β chain 0.98 0.98 0.90 2.86
3 ApoA-I ApoA-II 0.96 0.94 0.95 2.85
4 Fibrinogen α chain Fibrinogen γ chain 0.94 0.97 0.92 2.83
5 IgG h. chain V-III region BRO IgG κ chain C region 0.92 0.91 0.90 2.73
6 Complement factor B Histidine-rich glycoprotein 0.91 0.95 0.81 2.67
7 ApoA-IV Kallistatin 0.79 0.94 0.93 2.67
8 IgGγ-1 chain C region IgG κ chain C region 0.94 0.77 0.92 2.62
9 Complement C8 α Complement C8 β 0.99 0.88 0.74 2.61
10 Insulin-like growth factor-binding protein 1 Inter-α-trypsin inhibitor 4 0.87 0.99 0.76 2.61
11 Insulin-like growth factor-binding protein 1 Extracellular matrix protein 1 0.79 0.89 0.92 2.59
12 IgG κ chain C region IgG λ-1 chain C region 0.97 0.87 0.74 2.58
13 Complement factor I Hemopexin 0.92 0.92 0.73 2.56
14 Inter-α-trypsin inhibitor 1 Inter-α-trypsin inhibitor 2 0.94 0.99 0.59 2.51
15 Complement factor B n-acetylmuramoyl-l-ala. amid. 0.95 0.96 0.59 2.50
16 IgG γ-1 chain C region IgG λ-1 chain C region 0.91 0.75 0.84 2.50
17 IgG heavy chain V-III reg. BRO IgG γ-1 chain C region 0.82 0.83 0.79 2.44
18 Complement factor C4-B Complement C5 0.65 0.84 0.93 2.43
19 IgG κ chain C region IgG λ chain V-I region HA 0.87 0.76 0.80 2.43
20 IgG heavy chain V-III reg. BRO IgG λ-1 chain C region 0.89 0.80 0.72 2.41
21 IgG γ-1 chain C region IgG λ chain V-I region HA 0.84 0.86 0.70 2.41
22 IgG heavy chain V-III reg. BRO IgG λ chain V-I region HA 0.85 0.76 0.76 2.37
23 Complement C1s Complement factor C4-B 0.95 0.49 0.92 2.35
24 α-1-antichymotrypsin ApoJ 0.87 0.58 0.87 2.32
25 Complement factor B Coagulation factor XII 0.85 0.93 0.51 2.29
26 Carboxypeptidase B2 Kallistatin 0.83 0.92 0.53 2.27
27 Extracellular matrix protein 1 Inter-α-trypsin inhibitor 4 0.71 0.91 0.65 2.27
28 Histidine-rich glycoprotein n-acetylmuramoyl-l-ala. amid. 0.91 0.93 0.40 2.25
29 IgG λ-1 chain C region Ig λ chain V-I region HA 0.79 0.78 0.65 2.21
30 Antithrombin-III Pigment epithelial-derived factor 1.00 0.85 0.34 2.18
31 α-1-antichymotrypsin Kininogen-1 0.90 0.40 0.88 2.18
32 ApoA-II Extracellular matrix protein 1 0.48 0.83 0.87 2.18
33 α-1B-glycoprotein α-2-HS-glycoprotein 0.84 0.50 0.82 2.16
34 ApoH Plasminogen 0.83 0.90 0.42 2.15
35 ApoA-I Extracellular matrix protein 1 0.51 0.78 0.84 2.13
36 Complement C9 Heparin cofactor 2 0.39 0.80 0.91 2.09
37 ApoJ Inter-α-trypsin inhibitor 4 0.84 0.71 0.55 2.09
38 ApoA-I ApoM 0.73 0.53 0.82 2.08
39 Complement C1s Complement C5 0.44 0.74 0.90 2.08
40 α-1B-glycoprotein Coagulation factor XII 0.44 0.99 0.64 2.07
41 Antithrombin-III ApoA-IV 0.30 0.92 0.83 2.05
42 ApoA-II ApoM 0.72 0.44 0.87 2.04
43 ApoC-I Complement C7 0.67 0.64 0.72 2.03
44 Complement factor B Hemopexin 0.45 0.92 0.64 2.01
45 α-1B-glycoprotein n-acetylmuramoyl-l-ala. amid. 0.90 0.89 0.21 2.01
46 α-2-macroglobulin Ig μ chain C region 0.72 0.57 0.70 1.99
47 Coagulation factor XII Histidine-rich glycoprotein 0.66 0.84 0.48 1.98
48 Plasminogen Serotransferrin 0.98 0.73 0.27 1.98
49 ApoJ Haptoglobin 0.77 0.28 0.93 1.98
50 ApoA-IV Carboxypeptidase B2 0.46 0.88 0.63 1.97
79 ApoL-I Haptoglobin-related protein 0.72 0.70 0.39 1.81

a Composite score (i.e. sum of individual separation correlation scores).