eTable 2. Inclusion and exclusion criteria for abstracts and full-text articles in the systematic literature review.
| Inclusion criteria for abstracts and full text | |
| Population | Children and adolescents (<18 years) with fetal alcohol syndrome (fas) |
| Intervention | Diagnostic tests for the following criteria:
|
| Controls | Healthy children and adolescents Children and adolescents with a diagnosed neuropsychological disorder other than FAS (e.g., ADHD) Children and adolescents with partial FAS, alcohol-related neurodevelopmental disorders, and alcohol-related birth defects |
| End points | The principal end point was the diagnostic discrimination of the test procedures in relation to FAS; no other study parameters were defined |
| Study types | Inclusion of randomized controlled trials, secondary inclusion of cohort or case–control studies, case reports, case series (>10 patients), systematic reviews, and meta-analyses of these studies. Note: case series were excluded at the second, full-text inspection |
| Languages | English, German |
| Exclusion criteria for abstracts and full text | |
| E1 | Other disease |
| E2 | Studies on animals or in vitro |
| E3 | Other topic (not diagnosis of or screening for FAS) |
| E4 | Method of publication, other type of publication |
| E5 | Nonsystematic review |
| E6 | Probands predominantly (more than 80%) >18 years old |
| E7 | Regarding maternal alcohol consumption: publications before 2008 were excluded because of the existence of a systematic review by Elliot et al. (3) covering the literature up to July 2008 |
| E8 | Double publications (duplicates) |