Figure 8.

Reponses of the two-compartment NL model to 4 kHz input. (A) Two-compartment NL neuron model, with a soma and a node interconnected by an axonal conductance. The somatic compartment has the same amount of leak and low-voltage-activated potassium (K_LVA) conductances as the single compartment model. In addition to the leak and K_LVA, the nodal compartment has Na and high-voltage-activated potassium (K_HVA) conductances to generate spikes. (B) Spike rate of the model neuron plotted against the phase difference δ between ipsi- and contralateral model NM inputs. We define the spike rate with δ = 0 as the “in-phase rate,” and δ = ±π as the “out-of-phase rate.” In-phase and out-of-phase rates are plotted against the mean spike rate of NM fibers (C), the total number of NM fibers (D), the degree of phase-locking of the NM fibers (E), and the half peak width W of the unitary synaptic input conductance (F). Vertical broken gray lines in (C–F) show the default parameters (λ₀ = 500 Hz, M = 300 fibers, r = 0.6, W = 0.1 ms) used in our simulations.