Table 5.

Changes in Selenium Levels by Time and Treatment Arm

Change	Year 2–Baseline (n = 375)				Year 4–Baseline (n = 194)				Year 4–Year 2 (n = 164)
	Placebo		Selenium		Placebo		Selenium		Placebo		Selenium
	No. of Patients	%	No. of Patients	%	No. of Patients	%	No. of Patients	%	No. of Patients	%	No. of Patients	%
Decrease	44	32.4	5	2.1	27	36.5	1	0.8	21	36.2	11	10.4
No change	55	40.4	12	5.0	31	41.9	8	6.6	20	34.5	91	85.9
Increase	37	27.2	222	92.9	16	21.6	111	92.5	17	29.3	4	3.8