Table 3.
Association of Symptom Class Prevalence and Physical/Mental Component Summary of the Medical Outcomes Study 36-Item Short-Form Health Survey: Multivariable Analyses
| Variable | Physical Component Summary |
Mental Component Summary |
||||||
|---|---|---|---|---|---|---|---|---|
| Model 1/Model 2 |
Model 3 |
Model 1/Model 2 |
Model 3 |
|||||
| Beta | P | Beta | P | Beta | P | Beta | P | |
| Model 1 | ||||||||
| Age | −0.22 | < .001 | −0.08 | .009 | −0.14 | .002 | −0.02 | .623 |
| Sex (Reference: male) | −1.96 | < .001 | −0.39 | .228 | −2.94 | < .001 | −1.86 | < .001 |
| Race/ethnicity (Reference: white) | ||||||||
| Black | −1.14 | .127 | −1.80 | .001 | 0.35 | .651 | −0.59 | .288 |
| Hispanic | 1.57 | .261 | −0.38 | .698 | 2.64 | .068 | 0.66 | .524 |
| Other (NA, AS, PI, etc.) | 2.65 | .104 | 1.24 | .265 | 2.71 | .108 | 0.54 | .644 |
| Education (Reference: below HS) | ||||||||
| HS/GED | 3.75 | < .001 | 2.53 | < .001 | 3.03 | .002 | 1.66 | .015 |
| Training after HS/some college | 6.51 | < .001 | 4.07 | < .001 | 5.27 | < .001 | 2.94 | < .001 |
| College graduate | 8.49 | < .001 | 4.33 | < .001 | 7.17 | < .001 | 3.27 | < .001 |
| Post-graduate | 10.19 | < .001 | 4.86 | < .001 | 8.61 | < .001 | 3.35 | < .001 |
| Other | 3.65 | .001 | 3.03 | < .001 | 2.91 | .010 | 3.32 | < .001 |
| Years since diagnosis | 0.06 | .185 | 0.02 | .512 | 0.06 | .210 | <0.01 | .760 |
| Second cancer | −2.93 | < .001 | −0.85 | .060 | −2.06 | .002 | −0.41 | .389 |
| Chemotherapy | −0.36 | .607 | −1.05 | .029 | −0.24 | .738 | −0.77 | .132 |
| Radiotherapy | −1.86 | < .001 | −1.09 | .003 | −1.26 | .020 | −0.39 | .305 |
| Amputation | −3.02 | .016 | −1.27 | .141 | 0.03 | .984 | 1.14 | .212 |
| Model 2 | ||||||||
| Symptom class | ||||||||
| Cardiac symptoms | −4.12 | < .001 | −3.51 | < .001 | −2.27 | < .001 | −1.75 | < .001 |
| Pulmonary symptoms | −1.98 | .003 | −1.46 | .029 | −0.34 | .625 | −0.33 | .643 |
| Motor/movement problems | −4.36 | < .001 | −4.19 | < .001 | −0.99 | .044 | −0.94 | .055 |
| Pain in head | −1.41 | < .001 | −1.47 | < .001 | −2.59 | < .001 | −2.24 | < .001 |
| Pain in back/neck | −2.58 | < .001 | −2.53 | < .001 | −2.06 | < .001 | −2.06 | < .001 |
| Pain in other sites* | −3.30 | < .001 | −3.18 | < .001 | −1.92 | < .001 | −1.84 | < .001 |
| Sensation abnormalities | −1.81 | < .001 | −1.86 | < .001 | −1.31 | .001 | −1.38 | < .001 |
| Disfigurement | −2.48 | < .001 | −2.29 | < .001 | −2.08 | < .001 | −2.03 | < .001 |
| Learning/memory problems | −1.72 | < .001 | −1.47 | < .001 | −2.04 | < .001 | −1.49 | < .001 |
| Anxiety | −1.84 | .002 | −1.57 | .006 | −4.28 | < .001 | −4.25 | < .001 |
| Depression | −3.84 | < .001 | −3.88 | < .001 | −8.93 | < .001 | −9.22 | < .001 |
| Somatization | −4.96 | < .001 | −4.57 | < .001 | −3.13 | < .001 | −2.92 | < .001 |
| Variance, % | ||||||||
| Model 1 | 15.0 | 10.1 | ||||||
| Model 2 | 60.0 | 56.0 | ||||||
| Model 3 | 62.5 | 58.1 | ||||||
NOTE. Model 1 only includes demographic and clinical variables as independent variables; Model 2 only includes 12 symptom classes as independent variables; and Model 3 includes demographic and clinical variables plus 12 symptom classes as independent variables.
Abbreviations: AS, Asian; GED, general education development; HS, high school; NA, Native American; PI, Pacific Islander.
*
Pain involving sites other than head, neck, and back.
†
P < .05.
‡
P < .01.
§
P < .001.