Table 3. Quantification of total capillaries and capillaries containing bone marrow-derived GFP-positive-incorporated EPCs in the infarct zone.
No prior bone marrow transplantation |
Prior bone marrow transplantation |
|||
---|---|---|---|---|
Control MI (n=16) | AdA-I MI (n=16) | Control MI (n=16) | AdA-I MI (n=14) | |
Capillary density (number mm−2) | 145±16 | 197±19* | 144±14 | 198±21* |
GFP-positive capillary density (number mm−2) | N.A. | N.A. | 30.7±8.0 | 35.9±8.6 |
GFP-positive capillaries (% of total capillaries) | N.A. | N.A. | 19.3±4.2 | 18.0±3.4 |
Abbreviations: EPC, endothelial progenitor cell; GFP, green-fluorescent protein; MI, myocardial infarction; N.A., not applicable.
Data are expressed as means±s.e.m. *P<0.05 for control MI versus AdA-I MI.