A. Pim-1, Pim-2 and Pim-3 kinase expression in cell lines expressing ABCG2 or ABCB1 and parental cells was studied by immunoblotting, and GAPDH expression was measured as a loading control. A representative blot from three separate experiments is shown. * indicates a non-specific band. In the Pim-1 immunoblot a five-fold higher quantity of protein was loaded in the HL60, HL60/VCR, 8226 and 8226/MR20 lanes. B. Pim-1, Pim-2 and Pim-3 mRNA expression, measured by RT-PCR and normalized to GAPDH expression.