Skip to main content
. Author manuscript; available in PMC: 2013 Nov 9.
Published in final edited form as: Clin Cancer Res. 2012 Feb 28;18(8):10.1158/1078-0432.CCR-11-2830. doi: 10.1158/1078-0432.CCR-11-2830

Table 1. Patient and Clinical Characteristics by total cMET and phospho-cMET levels.

Overall
(N=257)
cMET p-cMET
High cMET
(>0)
(N=181)
Low cMET
(≤0)
(N=76)
High p-cMET
(>0.35)
(N=123)
Low p-cMET
(≤0.35)
(N=134)
N % N % N % P N % N % P
Age
≤ 50 128 49.8 83 45.9 45 59.2 0.069 49 39.8 79 59.0 0.003
>50 129 50.2 98 54.1 31 40.8 74 60.2 55 41.0
Stage
I 8 3.1 4 2.2 4 5.3 0.426 2 1.6 6 4.5 0.391
II 141 55.3 43 56.4 40 52.6 67 54.9 74 55.6
III 106 41.6 39 41.3 32 42.1 53 43.4 53 39.8
Grade
1 12 4.7 9 5.1 3 4.0 0.473 9 7.5 3 2.3 0.046
2 73 28.9 55 30.9 18 24.0 39 32.5 34 25.6
3 168 66.4 114 64.0 54 72.0 72 60.0 96 72.2
Chemotherapy
Anthracycline based 17 6.7 11 6.2 6 7.9 0.228 10 8.3 7 5.3 0.214
Taxane based 21 8.3 16 16.9 5 6.6 10 8.3 11 8.3
Anthracycline & Taxane 180 70.9 121 68.1 59 77.6 79 65.3 101 75.9
No Chemotherapy 36 14.1 30 16.8 6 7.9 22 18.2 14 10.5
Hormone Therapy
Yes 107 40.5 70 38.7 37 48.7 0.178 59 48.0 48 35.8 0.065
No 150 59.5 111 61.3 39 51.3 64 52.0 86 64.2
Radiation Therapy
Yes 164 63.8 108 59.7 56 73.7 0.046 79 64.2 85 63.4 0.998
No 93 36.2 73 40.3 20 26.3 44 35.8 49 36.6
Subtype
HER2-positive 53 20.6 40 22.1 13 17.1 0.079 25 20.3 28 20.9 0.064
HR-positive 140 54.5 103 56.9 37 48.7 75 61.0 65 48.5
Triple Negative 64 24.9 38 31.0 26 34.2 23 18.7 41 30.6

cMET: Total cMET, p-cMET: Phospho-cMET, HR-positive: Hormone receptor positive