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Model of a Cx43 gap junction channel and monomer. (A) The channel pore location has been indicated by the yellow circle. (B) The Cx43 monomer with protein partners. The abbreviations are as follows: NT, N-terminus; CL, cytoplasmic loop; CT, C-terminus; E1 and E2, extracellular loops 1 and 2; TM1-4, transmembrane segments 1-4.
