Table 2.

Fractal parameters of chromatin as prognostic factors in malignant neoplasias.

Neoplasia	Preparation	Image	Multivariate regression	Results	Ref.
Oral squamous cell carcinomas	Histology	Binarized	Yes	FD adverse prognostic factor (survival)	[108]
Larynx squamous cell carcinomas	Histology	Binarized	No	FD adverse prognostic factor (survival)	[104]
Cutaneous melanomas	Histology	Pseudo-3D	Yes	FD adverse prognostic factor (survival)	[113]
Myeloma	Cytology	Pseudo-3D	Yes	FD and goodness-of-fit adverse prognostic factors (survival)	[124]
Acute myeloid leukemia	Cytology	Pseudo-3D	Yes	Goodness-of-fit adverse prognostic factor (survival)	[132]
Acute precursor B lymphoblastic leukemia	Cytology	Pseudo-3D	Yes	Goodness-of-fit adverse prognostic factor (survival)	[131]
Meningiomas	Histology	Binarized	Yes	FD of contour adverse prognostic factors only in univariate analysis (recurrence)	[136]