Fig. 3.

Mean loss of total body weight, fat mass, lean mass, and bone mass measured by DXA in 12 severely hypothyroid patients (mean age = 55 years, serum TSH = 102 mU/l, fT₄ = 4.5 pmol/l, BMI = 28.5) over 1 year of L-T₄ replacement therapy. After 1 year, TSH was 2.2 mU/l, fT₄ was 18 pmol/l and BMI was 26.8. Data from Karmisholt et al. [45].