Table 2.

Reasons for nonadherent behavior of patients [45]

Patient-related factors	Therapy-related factors
• Low level of suffering	• Complexity of regimen
• Anxiety that therapy harms	• Side effects
• Anxiety that medication leads to nausea/vomiting, and so forth	• Long-term therapy
• Syringe phobia
• Negative experiences related to clinic or doctor
• Laziness, restrictions in intelligence or memory
Doctor–patient relationship	Institution
• Insufficient education and information	• Longer waiting times
• Dissatisfaction	• Insufficiently structured processes
• Long consultation interval