Table 1.
Parameter | Description | LHS range | PRCC |
---|---|---|---|
sP,TNF | Maximal number of TNF-α molecules that a phagocyte can secrete every 6-second time step | [0, 2.5] | −0.67 |
pT,P | Probability of moving a T cell onto a micro-compartment containing a phagocyte | [0.005, 0.05] | −0.61 |
pT,recr | Probability of recruiting a T cell | [0.05, 0.3] | −0.40 |
τP,TNF,NFκB | TNF-α level required for NFκB activation in phagocytes | [0.01, 0.1] | 0.36 |
pM,recr | Probability of recruiting a macrophage | [0.01, 0.1] | 0.32 |
Ncaseous | Number of killings for a microcompartment to become caseous | [5, 15] | −0.23 |
pT,T | Probability of moving a T cell onto a micro-compartment already containing a T cell | [0.01, 0.1] | −0.21 |