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Structure-based multiple sequence alignment of the QS LuxRs with the prototype of the PAB LuxR solos subfamily. The residues of the QS LuxR involved in ligand binding are colored in red. The homologous residues of OryR, the prototype of PAB LuxR solos subfamily, belonging to Cluster 1 are highlighted by a star while the ones belonging to Cluster 2 and Cluster 3 (see text) are highlighted in cyan and in green respectively.
