Table 3.
Ivabradine | Placebo | p | |
---|---|---|---|
MRI at hospital discharge | |||
Infarct size (g) | 13.7 (5.1;24.3) | 22.1 (12.0;29.9) | |
Number of patients | 24 | 13 | |
E (SE) (95% CI) | −7.5 (4.4) (−16.4–1.5) | 0.103 | |
Relative infarct size (% of LV mass) | 11.7 (4.3;16.5) | 18.1 (12.5;21.1) | |
Number of patients | 24 | 13 | |
E (SE) (95% CI) | −4.6 (3.4) (−11.4–2.3) | 0.190 | |
Area at risk (% of LV mass) | 24.4 (18.5;38.8) | 31.4 (23.0;39.4) | |
Number of patients | 15 | 10 | |
E (SE) (95% CI) | 1.0 (6.5) (−12.4–14.4) | 0.879 | |
Microvascular obstruction (g) | 4.1 (1.6;6.1) | 5.2 (1.8;7.1) | |
Number of patients | 8 | 6 | |
E (SE) (95% CI) | −2.6 (2.9) (−8.8–3.7) | 0.315 | |
Microvascular obstruction (% of LV mass) | 2.8 (1.3;5.8) | 4.0 (1.7;4.6) | |
Number of patients | 8 | 6 | |
E (SE) (95% CI) | −0.9 (1.9) (−5.1–3.3) | 0.617 | |
MRI at four months follow up | |||
Infarct size (g) | 8.7 (2.7;16.8) | 6.3 (5.1;18.7) | |
Number of patients | 24 | 12 | |
E (SE) (95% CI) | −1.2 (3.1) (−7.5–5.2) | 0.726 | |
Relative infarct size (% of LV mass) | 7.5 (2.5;17.6) | 5.8 (4.9;14.6) | |
Number of patients | 24 | 12 | |
E (SE) (95% CI) | 0.2 (2.9) (−5.8–6.2) | 0.945 |
CI: confidence interval; E: estimate; LV: left ventricular; SE: standard error.
Values are median (Q1;Q3) unless otherwise indicated.